Prebys Ventures

Overview

Prebys Ventures is a venture capital firm dedicated to fostering innovation and economic growth within the San Diego region. Operated by the Conrad Prebys Foundation, the firm focuses on early-stage investments in technology and life sciences companies that demonstrate potential for significant growth and community impact. By targeting startups that align with the foundation's mission, Prebys Ventures aims to strengthen the region's position as a global innovation hub. The firm's investment strategy emphasizes both financial returns and measurable positive impacts on the San Diego community. With a $50 million fund launched in February 2025, Prebys Ventures seeks to address a critical resource gap in the region's innovation ecosystem. The fund typically invests between $500,000 and $2 million in seed, Series A, and Series B rounds, often collaborating with other top-tier venture firms to syndicate deals and support portfolio companies. Led by Managing Director Mike Krenn, Prebys Ventures leverages an extensive network of life science and technology domain experts to provide strategic guidance and resources to its portfolio companies. The firm maintains a long-term view, reinvesting returns back into the regional economy to create a sustainable and exponentially growing vehicle that invests into the San Diego community in perpetuity. This approach reflects Prebys Ventures' commitment to driving lasting positive change and economic opportunity across the region. Investment Requirements: - Focus on early-stage companies in the technology and life sciences sectors. - Companies should be based in the San Diego region. - Alignment with the Conrad Prebys Foundation's mission to drive innovation and economic growth. Portfolio Companies: - Aero RX Therapeutics - Aspen Neuroscience - Condor - Crystalys Therapeutics - Protalys Therapeutics - Welby Health